Buy PT-141 2026 — Bremelanotide for melanocortin receptor (MC3R/MC4R) research (EU)
PT-141 at a glance
| Designation | PT-141 (Bremelanotide) |
|---|---|
| Identity | Synthetic cyclic heptapeptide, structurally derived from α-MSH |
| Synonyms | Bremelanotide, PT141 |
| Research context | Melanocortin receptor binding models (MC1R/MC3R/MC4R), CNS models (in-vitro/animal model) |
| CAS number | 189691-06-3 (the batch-specific COA is authoritative) |
| Molecular formula | C50H68N14O10 |
| Form | Lyophilised powder (freeze-dried), sealed vial |
| Amount | 10 mg per vial |
| Purity | ≥99% (HPLC), identity confirmed by LC-MS |
| Analysis | External third-party laboratory, batch-specific COA |
| Intended use | For Research Use Only (RUO) |
| Price | €59.90 · Shipping from Germany |
What is PT-141?
PT-141, with the international non-proprietary name Bremelanotide, is a synthetic Cyclic heptapeptide – a ring-closed peptide composed of seven amino acids. It is structurally derived from the sequence of the melanocortin peptide Alpha-MSH (alpha-melanocyte-stimulating hormone). Due to its cyclic architecture, PT-141 differs from linear peptides and is considered a well-characterised, defined reference substance from the melanocortin family in laboratory research. It is supplied as a stable lyophilised powder in a sealed vial (10 mg). CAS number (189691-06-3) and molecular formula (C50H68N14O10) are documented in the batch-related certificate of analysis.
Molecular profile & target structure
As a heptapeptide, PT-141 consists of seven amino acid building blocks, which are closed into a ring; the molecular formula C50H68N14O10 reflects this compact, nitrogen-rich structure. The structural similarity to Alpha-MSH places the substance into the context of the melanocortin system: In the literature, PT-141 is investigated as a ligand that binds to members of the Melanocortin receptor family binds – including MC1R, MC3R and MC4R. These receptors belong to the G-protein-coupled receptors. The combination of a defined, cyclic sequence and its relationship to a natural melanocortin peptide makes PT-141 a frequently used reference in receptor and neurobiological study models.
What in-vitro and animal model studies document
The following summary reflects only what is described in the publicly accessible preclinical literature – it is not a statement about an effect or suitability in humans.
- Melanocortin receptor binding: Published in vitro studies investigate PT-141 in binding models at melanocortin receptors, including MC1R, MC3R, and MC4R.
- ZNS Models: Several papers document observations of PT-141 in central nervous system (CNS) models, in which the melanocortin receptors of the species studied play a role.
- Receptor selectivity: Individual studies describe the binding profile of PT-141 across different melanocortin receptor subtypes as a model for ligand-receptor interaction.
- α-MSH-related The structural derivation of α-MSH is used as a starting point for the comparison of melanocortin ligands in biochemical studies.
These observations originate from in-vitro and animal models. They justify the research interest in PT-141, but do not make any statements regarding safety, efficacy, or any application outside of laboratory research.
Purity, COA & Analytical Testing
Purity and identity are the two values that count. HPLC demonstrates purity (target value ≥ 99 %), LC-MS confirms the identity via the molecular mass – for a cyclic heptapeptide like PT-141, the correct mass is an important proof of identity. Both values are stated in the batch-related COA. We explain how to read such a certificate in Understanding and reading a Certificate of Analysis (COA); the procedures themselves in Peptide Purity: HPLC and LC-MS Explained.
Storage & Handling
As a lyophilised product, PT-141 is stable when it is kept cool, dry and protected from light and stored – ideally at -20°C for longer storage. Please refer to the COA for batch-specific information. Principles: Storing and Handling Research Peptides.
Buying PT-141 in the EU – what matters
What matters is not the price, but this: Does the label match the contents? Here's what BlitzLab delivers on:
- Batch-specific COA from a third-party laboratory – HPLC (purity) and LC-MS (identity), carried out externally, not by us.
- EU Shipping, discreetly packaged, with tracking – usually 2–5 working days.
- Transparent RUO stance – clear labelling, complete Compliance page, no claims of efficacy or cure.
What else to look out for with a reputable provider: 7-point checklist.
Frequently asked questions about buying PT-141
Note on Sources & RUO
This guide summarises publicly available preclinical research literature (in vitro and animal models) on PT-141. The accompanying Certificate of Analysis is always authoritative for the identity, CAS number, molecular formula and purity of the supplied batch. All information is for informational purposes within a research context (Research Use Only) and does not constitute medical advice, dosage, or application recommendations.
Certificate of Analysis, specification, and availability directly on the product page.