Buy Semax 2026 — ACTH(4-10) analogue for BDNF/neurotrophic research (EU)

Peptide Research · 28 June 2026 · 11 min read · Research Use Only

Semax at a glance

What is Semax?

Semax is a synthetic Heptapeptide, which is derived from fragment 4–10 of adrenocorticotropic hormone (ACTH). An additional Pro-Gly-Pro-Rest is attached. This extension at the C-terminus distinguishes Semax from the native fragment and is described in the literature as a structural feature that makes the peptide readily accessible for analytical characterisation. Semax is supplied as a stable lyophilisate in a sealed vial (10 mg). In laboratory research, it serves as a defined reference substance. The CAS number is 80714-61-0; the molecular formula is documented in the batch-specific certificate of analysis.

Molecular profile & target structure

Semax is derived from a short, well-defined amino acid sequence: the ACTH fragment 4-10, supplemented with a Pro-Gly-Pro-Rest. As a synthetic heptapeptide, it possesses a precisely defined primary structure, which can be confirmed by LC-MS via its molecular mass. In the preclinical literature, Semax is frequently described as a model peptide with CNS relevance described because its sequence is derived from a native peptide fragment. The combination of a short, unambiguous sequence and good analytical characterisability makes the heptapeptide a frequently used reference in neurobiological study models. The definitive empirical formula of the supplied batch is stated in the COA.

What in-vitro and animal model studies document

The following summary reflects only what is described in the publicly accessible preclinical literature – it is not a statement about an effect or suitability in humans.

• Neurotrophic markers: Published studies investigate Semax in models relating to neurotrophic markers, including Brain-Derived Neurotrophic Factor (BDNF).
• ZNS cell models Several studies document observations on central nervous system cell models (in vitro).
• Animal models Individual preclinical animal model studies describe Semax in the context of neurobiological questions.
• Peptide characterisation: Semax is used as a reference in analytical and biochemical research as a defined heptapeptide.

These observations come from in-vitro and animal models. They provide the basis for research interest in Semax, but do not make any claims about safety, efficacy, or application outside of laboratory research.

Purity, COA & Analytical Testing

Purity and identity are the two values that count. HPLC demonstrates purity (target value ≥ 99 %), LC-MS confirms the identity via molecular mass. Both values are listed on the batch-related COA. We explain how to read such a certificate in Understanding and reading a Certificate of Analysis (COA); the procedures themselves in Peptide Purity: HPLC and LC-MS Explained.

Storage & Handling

As a lyophilisate, Semax is stable when stored is kept cool, dry and protected from light and stored – ideally at -20°C for longer storage. Please refer to the COA for batch-specific information. Principles: Storing and Handling Research Peptides.

Buying Semax in the EU – what matters

What matters is not the price, but this: Does the label match the contents? Here's what BlitzLab delivers on:

• Batch-specific COA from a third-party laboratory – HPLC (purity) and LC-MS (identity), carried out externally, not by us.
• EU Shipping, discreetly packaged, with tracking – usually 2–5 working days.
• Transparent RUO stance – clear labelling, complete Compliance page, no claims of efficacy or cure.

What else to look out for with a reputable provider: 7-point checklist.

Frequently asked questions about buying Semax

Note on Sources & RUO

This guide summarises publicly available, preclinical research literature (in-vitro and animal models) on Semax. The accompanying Certificate of Analysis is always authoritative for the identity, CAS number, molecular formula, and purity of the delivered batch. All information is provided for research purposes only and does not constitute medical advice, dosage, or usage recommendations.